Glucose Responsive Insulin (GRI) or Smart Insulin is a form of insulin designed to be administered into the body and react as needed, mimicking as closely as possible the function of naturally produced insulin. GRI is designed to work when blood glucose levels rise above healthy levels and to be inactive when blood glucose levels are in, or below, the standard value. GRI can respond to meal-induced rises in blood glucose more rapidly and naturally than conventional fast-acting insulins ultimately leading to improved glucose control and longer-term outcomes. GRI will not lead to insulin-mediated hypoglycaemia, which is one of the most feared and severe side effects of insulin treatment experienced by people with Type 1 Diabetes. See our Research and Subscribe to be kept up-to-date on the development of Glucose Responsive Insulin.