This clinical trial is testing a medication called hydroxychloroquine (HCQ) to assess safety and effectiveness in people at risk of developing T1D. The study is enrolling people with T1D autoantibodies confirmed by screening, to see if HCQ can prevent T1D developing. HCQ is used as a treatment for malaria, lupus, and rheumatoid arthritis. It has […]
BANDIT is a clinical trial testing a drug called baricitinib that has the potential to slow or stop the destruction of beta cells in people with T1D. Participants in the BANDIT trial must be between the ages of 12 – 30 years old, and must have been diagnosed with type 1 diabetes within the last 100 […]
This clinical trial is investigating whether fenofibrate, a drug used to lower cholesterol, can slow or reverse eye damage in adults with type 1 diabetes. Fenofibrate has been shown to slow eye damage in type 2 diabetes, and researchers are now investigating whether the same effect will be seen in T1D. This study has been […]
This study is testing whether a new tablet can help to treat kidney disease in people with T1D. This tablet blocks a key component of the pathway responsible for the oxidative stress that damages kidneys. Participants in this clinical trial will attend 10 study visits over 56 weeks. This study has been approved by the […]
Family members of people with T1D are at increased risk of developing the disease themselves. Type1Screen is a free screening service available to any family member of a person with T1D, that can find out a person’s risk of developing T1D. Those at increased risk will be offered the opportunity to enrol in trials of […]
Our researchers are looking for young people with type 1 diabetes with a HbA1c above 9% to be involved in a clinical trial of a new advanced hybrid closed-loop system. We want to see if using the closed-loop insulin delivery system will improve time in range and HbA1c in this group.