The JDRF CRN Symposium 2023 Program

Monday 24th and Tuesday 25th July 2023

Swissôtel Sydney, 68 Market Street, SYDNEY, NSW 2000

Monday 24th July

7:00 - 8:00
REGISTRATION OPEN
8.00 - 8.45WELCOME AND OPENING
• Mr Mike Wilson OAM, Chief Executive Officer JDRF Australia - Acknowledgement of country and welcome
• The Hon Mark Butler, Minister for Health and Aged Care - Opening address
• Young type 1 diabetes (T1D) research advocates
• Dr. Dorota Pawlak, Chief Scientific Officer JDRF Australia - Overview of the Type 1 Diabetes Clinical Research Network
• Prof. Mark Atkinson, Director, University of Florida Diabetes Institute - Introduction to the JDRF Clinical Research Network Symposium
8:45 - 10:30

PROGRESS TOWARDS EARLY DIAGNOSIS
AND PRIMARY PREVENTION

Then and now


Moderator: Dr Megan Penno

KEYNOTE SPEAKERS
• Patient voice
• Prof Jennifer Couper - The first 1000 Days
• Prof Marian Rewers - Paradigm shifts in prevention and treatment of T1D

RAPID FIRE presentations
• Prof John Wentworth - An overview of the Type1Screen program since its inception in 2019
• Dr Kirstine Bell - Paving the way towards a national screening program for type 1 diabetes all Australian children
• A/Prof Emma Hamilton-Williams - Targeting the gut microbiota to prevent type 1 diabetes
• Dr Ki Wook Kim - Antiviral vaccines for primary prevention of type 1 diabetes
10.30 - 10.50
MORNING TEA AND NETWORKING BREAK
10:50 - 12:20

PANEL DISCUSSION - PRIMARY PREVENTION IN T1D,
COLLABORATIVE SOLUTIONS AND FUTURE DIRECTIONS


Moderator: Dr Kirstine Bell

EXPERT PANEL
Prof Marian Rewers, Prof Jennifer Couper, Prof Edwin Kirk AO, A/Prof John Wentworth, Prof Maria Craig, Prof William Rawlinson, Ms Melanie Cullen, Ms Renza Scibilia, Dr Gina Agiostratidou

RECAP OF MORNING SESSION
Highlights, learnings, barriers and where to next in early diagnosis and prevention
Presenter: A/Prof Emma Hamilton-Williams
12:20 - 12:50
LUNCH AND NETWORKING BREAK
12:50 - 15:30

INTERCEPTING AND DELAYING
THE COURSE OF T1D DEVELOPMENT

Disease Modifying Therapies


Moderator: A/Prof Stuart Mannering

KEYNOTE SPEAKERS
• Patient voice
• Prof Colin Dayan - Moving towards insulin-free T1D....what is stopping us?
• Prof Thomas Kay - The BANDIT trial - where to next?
• Dr Leni (Eleanor) Ramos - Disease modifying therapies - Teplizumab

HOT TOPIC PRESENTATIONS
• Prof Ranjeny Thomas AM – New therapies/learnings from other autoimmune diseases
• Dr Irina Buckle – RAGE targeted therapies for T1D prevention
• Prof Helen Thomas – JAK inhibitors/ target validation/BANDIT
• Dr Andrew Sutherland - Contemporary immunology of T1D: exploring new frontiers and opportunities
15:30 - 15:45
AFTERNOON TEA
15:45 - 17:00​PANEL DISCUSSION - OPPORTUNITIES AND BARRIERS OF EXPANDING THE NUMBER OF DISEASE MODIFYING THERAPIES TO T1D PATIENTS AT ALL DISEASE STAGES

Moderator: Prof Josephine Forbes

EXPERT PANEL
Prof Tom Kay, Prof Colin Dayan, Prof Ranjeny Thomas AM, Prof Kim Donaghue, Prof Simon Barry, Prof Fabienne Mackay, Ms Christine Garberg, Dr Elanor Ramos, Dr Sanjoy Dutta, Dr Katja Beitat

RECAP OF AFTERNOON SESSION
Highlights, learnings, barriers and new directions in intercepting and delaying the course of T1D development.
Presenter: A/Prof Tony Hunyh
17:00 - 19:00WELCOME & NETWORKING FUNCTION (including Symposium Cocktail function and Awards)
Presented by the JDRF Australia Research Committee

 

Tuesday 25th July

7:45 - 8:30MEETING THE EXPERTS AND FUNDING PARTNERS - Early career researcher’s breakfast

Moderator: Dr Dorota Pawlak

EXPERT PANEL
Prof Colin Dayan, Prof Marian Rewers, Prof Jennifer Couper, Prof Thomas Kay, Dr Leni (Eleanor) Ramos, Prof Natasha Rogers, Prof Timothy Jones, Prof Louise Maple-Brown, Prof Fabienne Mackay, Prof Philip O'Connell, Prof Shane Grey, Prof Peter Thorn, Dr Sanjoy Dutta, Dr Gina Agiostratidou
8:40 - 10:35

BETA CELL REPLACEMENT AND REGENERATION



MORNING WELCOME
Dr Dorota Pawlak

Moderator: Dr Aveni Haynes

KEYNOTE SPEAKERS
• Patient voice
• Prof Mark Atkinson - Lessons from nPOD and the Human Islet Network
• Prof Natasha Rogers - Tailoring the success of islet transplantation
• Prof Shane Grey - From the silk road to human trial – gene therapy for type 1 diabetes?


PECHAKUCHA STYLE PRESENTATIONS
• Dr Jacqui Schiesser – Stem cells
• Prof Peter Thorn - How to improve beta cell function within an implant
• Prof Sam El-Osta - EZH2 Inhibition influences pancreatic progenitor capacity
• Prof Anand Hardikar - Bio-markers of beta cell decline
10:35 - 11:00
MORNING TEA AND NETWORKING BREAK
11:00 - 12:30PANEL DISCUSSION - BETA CELL REPLACEMENT AND REGENERATION PANEL DISCUSSION

Moderator: Prof Toby Coates

EXPERT PANEL
Prof Philip O'Connell, Prof Wayne Hawthorne, Prof Stephen Alexander, Prof Shane Grey, A/Prof Jane Holmes-Walker, Prof Peter Thorn, Prof Sof Andrikopoulos, Dr John Males, Mr John Waszczuk

RECAP OF MORNING SESSION
Highlights, learnings, barriers and future directions in beta cell replacement and regeneration
Presenter: Prof Natasha Rogers
12:30 - 13:00
LUNCH AND NETWORKING BREAK
13:00 - 15:20

TECHNOLOGIES, ADJUNCT THERAPIES, ADOPTION AND POLICY


Moderator: Dr Mary Abraham

KEYNOTE SPEAKERS
• Patient voice
• Prof Jeffrey Braithwaite – Implementation, adoption and policy in the health system of 2030
• Prof Mark Cooper AO – Adjunct therapies
• A/Prof Sybil McAuley - Advanced Technologies
• Prof Timothy Jones – Equity of access
• Prof Louise Maple-Brown – Challenges of T1D care/disadvantaged and remote populations
• Prof Joshua Byrnes - Applied Health Economics
• Prof Jane Speight – Quality of life matters in the use of glycaemic technologies
15:20 - 15:35​
AFTERNOON TEA AND NETWORKING BREAK
15:35 - 17:00

PANEL DISCUSSION - EMBEDDING NEW THERAPIES AND NEW TECHNOLOGIES ACROSS T1D PATIENTS OF ALL AGES


Moderator: Prof Elif Ekinci

EMBEDDING NEW THERAPIES AND NEW TECHNOLOGIES ACROSS T1D PATIENTS OF ALL AGES – PANEL DISCUSSION
• Screening
• Replacement therapies
• Repurposed drugs
• Adjunct therapies
• Advanced technologies

EXPERT PANEL
Prof Jeffrey Braithwaite, Prof Mark Cooper AO, A/Prof Sybil McAuley, Prof Timothy Jones, Prof Louise Maple-Brown, Prof Joshua Byrnes, Prof Jane Speight, Mr Jonathan Salmon, Prof Fergus Cameron, Dr Laura Knecht, Dr Ben Nash

RECAP of all themes
Highlights, learnings, barriers and where to next in implementation of outcomes in T1D – advanced technologies, adjunct therapies, adoption, and policy
Presenter: Prof Elizabeth Davis
17:00CLOSING
Dr Dorota Pawlak