Summary of Emerging COVID-19/T1D Research

The first clinical paper looked at the whole English population to find an association between having diabetes (type 1 or type 2) and the risk of dying from COVID-19 in hospital. It found that:

– People living with diabetes faced a significantly higher risk of dying from COVID-19 in hospital in comparison to the rest of the population, and people with type 1 diabetes were at greater risk than those with type 2.

– There are a number of possible reasons for the difference between type 1 and type 2, including different patterns of complications, treatments and causes, as well as different frequencies of hypoglycaemia and hyperglycaemia

– Even with the additional risk associated with T1D or T2D, people under the age of 40 years with either type of diabetes were at very low absolute risk of dying from COVID-19

The second paper looked exclusively at people with diabetes (type 1 or type 2), to try to understand the COVID-19 risk factors within this group. The paper found:

– People with HbA1c above 86mmol/mol (or 10%) have a higher risk of dying compared to those with HbA1c 48-53mmol/mol (or 6.5-7%)

– Those with a BMI under 20, or over 40, have a higher risk of dying compared to those with a BMI between 25-30

– Those with impaired kidney function have a higher risk of dying compared to those with normal kidney function

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