IAA trial – Abatacept combined with nasal insulin in recently-diagnosed type 1 diabetes

IAA is a randomised controlled trial testing whether the combination of two safe immune therapies called abatacept and nasal insulin slows down the immune attack on the insulin producing (beta) cells of people with newly-diagnosed type 1 diabetes. If effective, the combination of these two therapies could delay the need for insulin injections. Approximately 60 participants will receive abatacept in combination with either nasal insulin or placebo over a 48-week period. Participants will be required to attend their local trial centre 17 times over two years, with majority of visits lasting less than one hour.

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